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ꯄ꯭ꯔꯗꯛꯇ ꯗꯤꯁ꯭ꯛꯔꯤꯄꯁꯟ꯫

ꯁꯣꯔꯁ ꯑꯃꯁꯨꯡ ꯄ꯭ꯔꯗꯛꯁꯅꯒꯤ ꯊꯧꯑꯣꯡ꯫
ꯑꯉ꯭ꯒꯨꯔꯒꯤ ꯈꯣꯡꯎꯞ ꯑꯦꯛꯁꯠꯔꯦꯛꯇ ꯑꯁꯤ ꯄꯨꯅꯤꯀꯥ ꯒ꯭ꯔꯦꯅꯦꯇꯝ ꯑꯦꯜ.(ꯏꯃꯨꯡ ꯂꯥꯏꯊ꯭ꯔꯦꯁꯤꯌꯥ)ꯒꯤ ꯁꯨꯡꯕꯥ ꯈꯣꯡꯎꯄꯇꯒꯤ ꯂꯧꯏ꯫ ꯃꯁꯤ ꯏꯊꯥꯅꯣꯜ ꯑꯦꯛꯁꯠꯔꯥꯛꯁꯟ, ꯃꯥꯏꯛꯔꯣꯋꯦꯕ-ꯑꯦꯁꯤꯁ꯭ꯇꯦꯗ ꯑꯦꯛꯁꯠꯔꯥꯛꯁꯟ, ꯅꯠꯠꯔꯒꯥ ꯁꯨꯄꯔꯛꯔꯤꯇꯤꯀꯦꯜ ꯁꯤ.ꯑꯣ.꯲ ꯑꯦꯛꯁꯠꯔꯥꯛꯁꯟ ꯇꯦꯛꯅꯤꯀꯁꯤꯡ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯔꯤꯐꯥꯏꯟꯗ ꯇꯧꯏ꯫ ꯑꯦꯛꯇꯤꯕ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯤ ꯂꯦꯞꯄꯥ ꯂꯩꯇꯕꯥ ꯃꯒꯨꯟ ꯑꯃꯁꯨꯡ ꯇꯪꯗꯨ ꯂꯩꯇꯥꯕꯥ ꯁꯣꯌꯗꯅꯥ ꯂꯩꯍꯟꯅꯕꯥ ꯃꯦꯟꯌꯨꯐꯦꯀꯆꯔꯤꯡ ꯄ꯭ꯔꯣꯁꯦꯁ ꯑꯁꯤ ꯖꯤ.ꯑꯦꯝ.ꯄꯤ.ꯒꯤ ꯁ꯭ꯇꯦꯟꯗꯔꯗꯁꯤꯡꯒꯥ ꯑꯀꯅꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯉꯥꯛꯅꯥ ꯆꯠꯂꯤ꯫

ꯀꯣꯔ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ꯫

ꯏꯂꯥꯖꯤꯛ ꯑꯦꯁꯤꯗ: ꯱.ꯑꯦꯟꯇꯤ-ꯀꯦꯟꯁꯔ, ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ, ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯁꯤꯡ ꯎꯠꯂꯤ; ꯃꯤꯑꯣꯏꯕꯒꯤ ꯄꯦꯄꯤꯂꯣꯃꯥ ꯚꯥꯏꯔꯁ (ꯑꯩꯆ.ꯄꯤ.ꯚꯤ.) ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.ꯒꯤ ꯔꯤꯞꯂꯤꯀꯦꯁꯟ ꯕ꯭ꯂꯣꯛ ꯇꯧꯕꯥ ꯑꯃꯁꯨꯡ ꯕ꯭ꯔꯦꯁ꯭ꯠ ꯑꯃꯁꯨꯡ ꯄ꯭ꯔꯣꯁ꯭ꯇꯦꯠ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ ꯊꯤꯡꯕꯗꯥ ꯎꯠꯂꯦ꯫

ꯄꯨꯅꯤꯀꯦꯂꯒꯤꯟ: ꯱.ꯚꯤꯇꯥꯃꯤꯟ ꯁꯤꯒꯤ ꯆꯥꯎꯔꯥꯛꯅꯥ ꯁꯔꯨꯛ ꯲꯰ ꯍꯦꯟꯅꯥ ꯐ꯭ꯔꯤ ꯔꯦꯗꯤꯀꯦꯜ ꯁ꯭ꯀꯦꯚꯦꯟꯖꯤꯡ ꯀꯦꯄꯥꯁꯤꯇꯤ ꯂꯩꯕꯥ ꯃꯄꯥꯉ꯭ꯒꯜ ꯀꯅꯕꯥ ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ ꯑꯃꯥ; ꯀꯥꯔꯗꯤꯑꯣꯚꯥꯁ꯭ꯀꯨꯂꯥꯔ ꯄ꯭ꯔꯣꯇꯦꯛꯁꯟ ꯑꯃꯁꯨꯡ ꯀꯣꯒꯅꯤꯇꯤꯕ ꯏꯝꯞꯔꯨꯚꯃꯦꯟꯇꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ꯫

ꯄꯣꯂꯤꯐꯦꯅꯣꯂꯁꯤꯡ: ꯱.ꯑꯦꯟꯇꯤ-ꯏꯅꯐ꯭ꯂꯦꯃꯦꯇꯔꯤ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯚꯥꯏꯔꯦꯜ ꯏꯐꯦꯛꯇꯁꯤꯡ ꯁꯤꯅꯦꯔꯖꯤꯁ꯭ꯇꯤꯛ ꯑꯣꯏꯅꯥ ꯍꯦꯅꯒꯠꯍꯅꯕꯥ ꯉꯝꯕꯥ ꯒ꯭ꯌꯥꯂꯤꯛ ꯑꯦꯁꯤꯗ, ꯀꯦꯇꯦꯆꯤꯟ ꯑꯃꯁꯨꯡ ꯑꯇꯩꯁꯤꯡ ꯌꯥꯎꯏ꯫

ꯄꯣꯠꯊꯣꯛꯀꯤ ꯀꯥꯟꯅꯕꯥ꯫

ꯃꯜꯇꯤ-ꯇꯥꯔꯒꯦꯠ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯁꯤꯡ꯫

ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ & ꯑꯦꯟꯇꯤ-ꯏꯅꯐ꯭ꯂꯦꯃꯦꯇꯔꯤ:12.5–25 mg/mL (ꯁ꯭ꯇꯦꯟꯗꯔꯗ ꯒ꯭ꯔꯦꯗ)ꯒꯤ MIC ꯚꯦꯜꯌꯨꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯁ꯭ꯇꯦꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ, ꯏ.ꯀꯣꯂꯤ, ꯑꯃꯁꯨꯡ ꯚꯥꯏꯕ꯭ꯔꯤꯑꯣ ꯄꯦꯔꯥꯍꯦꯃꯣꯂꯥꯏꯇꯤꯀꯁꯄꯨ ꯊꯤꯡꯏ; ꯄ꯭ꯔꯣꯄꯤꯑꯣꯅꯤꯕꯦꯛꯇꯦꯔꯤꯌꯝ ꯑꯦꯛꯅꯦꯁꯀꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.

ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ: ꯱.DPPH ꯐ꯭ꯔꯤ ꯔꯦꯗꯤꯀꯦꯜ ꯁ꯭ꯀꯦꯚꯦꯟꯖꯤꯡ ꯔꯦꯠ ꯑꯁꯤ 4 mg/mL ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟꯗꯥ 70.6% ꯌꯧꯏ; ꯂꯤꯄꯤꯗ ꯄꯦꯔꯣꯛꯁꯤꯗꯦꯁꯟ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯑꯁꯤ ꯒ꯭ꯔꯤꯟ ꯇꯤ ꯄꯣꯂꯤꯐꯦꯅꯣꯂꯁꯤꯡꯗꯒꯤ ꯍꯦꯜꯂꯤ꯫

ꯑꯦꯟꯇꯤꯀꯦꯟꯁꯔ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ: ꯱.ꯀꯣꯂꯣꯟ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯗꯥ ꯑꯦꯄꯣꯄꯇꯣꯁꯤꯁ ꯊꯣꯀꯍꯜꯂꯤ ꯑꯃꯁꯨꯡ ꯇꯤꯎꯃꯔ ꯑꯦꯟꯖꯤꯑꯣꯖꯦꯅꯦꯁꯤꯁ ꯊꯤꯡꯏ; ꯄ꯭ꯔꯤꯛꯂꯤꯅꯤꯀꯦꯜ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯅꯥ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯁꯣꯂꯤꯗ ꯇꯤꯎꯃꯔꯁꯤꯡꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯎꯠꯂꯤ꯫

ꯁꯦꯐꯇꯤ ꯚꯦꯔꯤꯐꯤꯀꯦꯁꯟ ꯇꯧꯕꯥ꯫
ꯑꯦꯛꯌꯨꯠ ꯑꯣꯔꯦꯜ ꯇꯣꯛꯁꯤꯁꯤꯇꯤ ꯇꯦꯁ꯭ꯇꯁꯤꯡꯅꯥ LD5 > 5000 mg/kg (ꯃꯥꯏꯁ) ꯎꯠꯂꯤ, ꯃꯁꯤꯗꯥ ꯖꯤꯅꯣꯇꯣꯛꯁꯤꯁꯤꯇꯤ ꯅꯠꯠꯔꯒꯥ ꯇꯦꯔꯥꯇꯣꯖꯦꯅꯤꯁꯤꯇꯤꯒꯤ ꯈꯨꯗꯝ ꯑꯃꯠꯇꯥ ꯂꯩꯇꯦ꯫
ꯑꯥꯏ.ꯑꯦꯁ.ꯑꯣ.꯹꯰꯰꯱, ꯌꯨ.ꯑꯦꯁ.ꯗꯤ.ꯑꯦ.ꯒꯤ ꯑꯣꯔꯒꯥꯅꯤꯛ, ꯏ.ꯌꯨ.ꯒꯤ ꯑꯣꯔꯒꯥꯅꯤꯛ, ꯀꯣꯁꯔ, ꯑꯃꯁꯨꯡ ꯍꯂꯥꯜ ꯁ꯭ꯇꯦꯟꯗꯔꯗꯀꯤ ꯃꯈꯥꯗꯥ ꯁꯔꯇꯤꯐꯥꯏꯗ ꯇꯧꯔꯕꯥ꯫

ꯄꯥꯛ ꯆꯥꯎꯔꯕꯥ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡ꯫

ꯐꯥꯔꯃꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯜ ꯒ꯭ꯔꯦꯗ: ꯱.ꯑꯦꯟꯇꯤ-ꯑꯩꯆ.ꯄꯤ.ꯚꯤ.ꯒꯤ ꯖꯦꯂꯁꯤꯡ, ꯍꯦꯄꯥꯇꯣꯞꯔꯣꯇꯦꯛꯇꯤꯕ ꯀꯦꯄꯁꯨꯂꯁꯤꯡ, ꯑꯃꯁꯨꯡ ꯀꯦꯟꯁꯔꯒꯤꯗꯃꯛꯇꯥ ꯑꯦꯗꯖꯨꯀꯦꯠ ꯊꯦꯔꯥꯄꯤꯁꯤꯡ ꯁꯦꯝꯕꯗꯥ ꯁꯤꯖꯤꯟꯅꯩ꯫

ꯀꯁꯃꯦꯇꯤꯛ ꯒ꯭ꯔꯦꯗ: ꯱.ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ, ꯋꯥꯏꯇꯤꯡ, ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤ-ꯑꯦꯖꯤꯡ ꯏꯅꯒ꯭ꯔꯦꯗꯤꯌꯦꯟꯇ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯏ; ꯆꯥꯏꯅꯥꯗꯥ ꯂꯩꯔꯤꯕꯥ ꯀꯁꯃꯦꯇꯤꯛ ꯏꯅꯒ꯭ꯔꯦꯗꯤꯌꯦꯟꯇꯁꯤꯡꯒꯤ ꯏꯅꯚꯦꯟꯇꯔꯤ (ꯑꯥꯏ.ꯏ.ꯁꯤ.ꯑꯥꯏ.ꯁꯤ.)ꯗꯥ ꯂꯤꯁ꯭ꯠ ꯇꯧꯕꯥ; ꯌꯨ.ꯚꯤ.-ꯅꯥ ꯊꯣꯀꯍꯅꯕꯥ ꯈꯣꯡꯗꯥ ꯑꯃꯥꯡ-ꯑꯇꯥ ꯍꯟꯊꯍꯟꯅꯕꯥ ꯂꯣꯔꯤꯑꯦꯜ ꯀ꯭ꯂꯤꯅꯤꯀꯦꯜ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯅꯥ ꯚꯦꯂꯤꯗꯦꯠ ꯇꯧꯈꯤ꯫

ꯂꯧꯎ-ꯁꯤꯡꯎꯒꯤ ꯒ꯭ꯔꯦꯗ: ꯱.ꯃꯅꯥ-ꯃꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯎꯍꯩ-ꯋꯥꯍꯩꯁꯤꯡꯗꯥ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯑꯦꯄꯜ ꯔꯤꯡ ꯔꯣꯠ) ꯐꯉ꯭ꯒꯦꯜ ꯂꯥꯌꯅꯥꯁꯤꯡꯒꯤꯗꯃꯛ ꯕꯥꯏꯑꯣꯄꯦꯁ꯭ꯇꯤꯁꯥꯏꯗ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯁꯤꯖꯤꯟꯅꯩ, ꯃꯁꯤꯅꯥ ꯀꯦꯃꯤꯀꯦꯜ ꯄꯦꯁ꯭ꯇꯤꯁꯥꯏꯗ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯍꯟꯊꯍꯜꯂꯤ꯫

ꯄ꯭ꯔꯗꯛꯇ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡ꯫

ꯐꯥꯔꯃꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯜ ꯑꯃꯁꯨꯡ ꯍꯦꯜꯊꯀꯦꯌꯔ꯫

ꯇꯣꯄꯤꯀꯦꯜ ꯐꯣꯔꯃꯨꯂꯦꯁꯅꯁꯤꯡ: ꯱.ꯁ꯭ꯀꯤꯟ ꯏꯅꯐ꯭ꯂꯦꯃꯦꯁꯟ (ꯑꯦꯀꯖꯤꯃꯥ, ꯑꯦꯛꯅꯤ) ꯑꯃꯁꯨꯡ ꯑꯣꯔꯦꯜ ꯑꯂꯁꯔ ꯂꯥꯌꯦꯡꯕꯗꯥ ꯁꯤꯖꯤꯟꯅꯩ, ꯃꯁꯤꯒꯤ ꯀ꯭ꯂꯤꯅꯤꯀꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯑꯁꯤ ꯸꯵%ꯗꯒꯤ ꯍꯦꯜꯂꯤ꯫

ꯃꯤꯠꯀꯤ ꯍꯤꯗꯥꯀꯁꯤꯡ: ꯱.ꯀ꯭ꯔꯣꯅꯤꯛ ꯍꯦꯄꯥꯇꯥꯏꯇꯤꯁ (ALTꯒꯤ ꯆꯥꯡ ꯍꯟꯊꯍꯅꯕꯥ), ꯗꯥꯏꯑꯦꯕꯦꯇꯤꯖ (ꯏꯅꯁꯨꯂꯤꯟ ꯁꯦꯟꯁꯤꯇꯤꯚꯤꯇꯤ ꯐꯒꯠꯍꯅꯕꯥ), ꯑꯃꯁꯨꯡ ꯍꯥꯏꯄꯔꯂꯤꯄꯤꯗꯦꯃꯤꯌꯥ ꯃꯦꯅꯦꯖ ꯇꯧꯕꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ꯫

ꯑꯦꯟꯇꯤꯚꯥꯏꯔꯦꯜ ꯔꯤꯁꯔꯆ: ꯱.ꯏꯅꯐ꯭ꯂꯨꯑꯦꯟꯖꯥ ꯑꯃꯁꯨꯡ ꯍꯔꯄꯤꯁ ꯁꯤꯝꯄꯂꯛꯁ ꯚꯥꯏꯔꯁ (HSV)ꯒꯤ ꯔꯤꯞꯂꯤꯀꯦꯁꯟ ꯊꯤꯡꯕꯥ ꯉꯝꯃꯤ ꯍꯥꯌꯅꯥ ꯎꯠꯂꯤ, ꯃꯁꯤꯗꯥ ꯑꯥꯏ.ꯁꯤ.55ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ ꯑꯁꯤ 0.5–2 mg/mLꯒꯤ ꯃꯔꯛꯇꯥ ꯂꯩ꯫

ꯀꯁꯃꯦꯇꯤꯛꯁ ꯑꯃꯁꯨꯡ ꯄꯔꯁꯣꯅꯦꯜ ꯀꯦꯌꯔ꯫

ꯁ꯭ꯀꯤꯅꯀꯦꯌꯔꯒꯤ ꯄꯣꯠꯊꯣꯀꯁꯤꯡ: ꯱.ꯌꯨ.ꯚꯤ.-ꯅꯥ ꯊꯣꯀꯍꯅꯕꯥ ꯑꯣꯛꯁꯤꯗꯦꯇꯤꯕ ꯁ꯭ꯠꯔꯦꯁ ꯍꯟꯊꯍꯟꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯈꯣꯡꯒꯤ ꯑꯍꯜ ꯑꯣꯏꯔꯀꯄꯥ ꯊꯦꯡꯊꯍꯟꯅꯕꯥ ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ ꯁꯦꯔꯥꯝ ꯑꯃꯁꯨꯡ ꯅꯨꯃꯤꯠꯀꯤ ꯃꯉꯥꯂꯗꯥ ꯁꯤꯖꯤꯟꯅꯩ (ꯑꯦꯜ.ꯑꯣꯔꯤꯑꯦꯜ ꯔꯤꯁꯔꯆꯅꯥ ꯑꯦꯝ.ꯑꯦꯝ.ꯄꯤ.-꯱ ꯀꯣꯂꯥꯖꯦꯅꯦꯖ ꯑꯦꯛꯁꯞꯔꯦꯁꯅꯒꯤ ꯗꯥꯎꯅꯔꯦꯒꯨꯂꯦꯁꯟ ꯎꯠꯂꯤ)꯫

ꯑꯣꯔꯦꯜ ꯀꯦꯌꯔ: ꯱.ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤ-ꯏꯅꯐ꯭ꯂꯦꯃꯦꯇꯔꯤꯒꯤ ꯄꯥꯟꯗꯃꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯃꯥꯎꯊꯋꯥꯁ ꯑꯃꯁꯨꯡ ꯇꯨꯊꯄꯦꯁ꯭ꯇꯇꯥ ꯁꯦꯝꯕꯥ, ꯄꯤꯔꯤꯌꯗꯟꯇꯜ ꯗꯤꯖꯤꯖ ꯉꯥꯀꯊꯣꯀꯄꯥ꯫

ꯍꯦꯌꯥꯔ ꯀꯦꯌꯔ: ꯱.ꯏꯅꯍꯤꯕꯤꯠ ꯇꯧꯅꯕꯥ ꯁ꯭ꯀꯦꯂꯞ ꯇꯣꯅꯤꯀꯁꯤꯡꯗꯥ ꯁꯤꯖꯤꯟꯅꯩ꯫ꯃꯥꯂꯥꯁꯦꯖꯤꯌꯥ꯫ꯑꯃꯁꯨꯡ ꯈꯣꯡꯎꯄꯀꯤ ꯀꯟꯗꯤꯁꯅꯁꯤꯡ ꯐꯒꯠꯍꯅꯕꯥ꯫

ꯐꯨꯗ ꯑꯃꯁꯨꯡ ꯗꯥꯏꯑꯦꯇꯔꯤ ꯁꯞꯂꯤꯃꯦꯟꯇꯁꯤꯡ꯫

ꯐꯉ꯭ꯀꯁꯅꯦꯜ ꯐꯨꯗꯁꯤꯡ: ꯱.ꯏꯝꯝꯌꯨꯅꯤꯇꯤ ꯍꯦꯅꯒꯠꯍꯟꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯒꯠ ꯃꯥꯏꯛꯔꯣꯕꯥꯏꯑꯣꯇꯥ ꯔꯤꯒꯨꯂꯦꯠ ꯇꯧꯅꯕꯥ ꯁꯣꯂꯤꯗ ꯕꯦꯚꯥꯔꯦꯖꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯆꯦꯅꯕꯥ ꯇꯦꯕꯂꯁꯤꯡꯗꯥ ꯍꯥꯄꯆꯤꯜꯂꯤ꯫

ꯅꯦꯆꯔꯦꯜ ꯄ꯭ꯔꯤꯖꯥꯔꯕ ꯇꯧꯕꯥ ꯌꯥꯕꯥ:ꯁꯤꯟꯊꯦꯇꯤꯛ ꯄ꯭ꯔꯤꯖꯥꯔꯕꯦꯇꯤꯕꯁꯤꯡ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯁꯣꯗꯤꯌꯝ ꯕꯦꯟꯖꯣꯑꯦꯠ)ꯒꯤ ꯃꯍꯧꯁꯥꯒꯤ ꯑꯣꯏꯕꯥ ꯑꯂꯇꯔꯅꯦꯇꯤꯕ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯖꯨꯁ ꯑꯃꯁꯨꯡ ꯃꯅꯥ-ꯃꯁꯤꯡꯒꯤ ꯄꯣꯠꯊꯣꯀꯁꯤꯡꯒꯤ ꯁꯦꯂꯐꯝ ꯍꯦꯅꯒꯠꯍꯜꯂꯤ; ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯎꯠꯂꯤ꯫ꯕꯦꯁꯤꯂꯁ ꯁꯦꯔꯤꯌꯁ꯫1 mg/mLꯗꯥ ꯌꯥꯎꯏ꯫

ꯍꯀꯁꯦꯂꯒꯤ ꯁꯞꯂꯤꯃꯦꯟꯇꯁꯤꯡ: ꯱.ꯑꯦꯛꯁꯔꯁꯥꯏꯖ-ꯅꯥ ꯊꯣꯀꯍꯅꯕꯥ ꯃꯁꯂꯁꯤꯡꯗꯥ ꯑꯃꯥꯡ-ꯑꯇꯥ ꯑꯃꯁꯨꯡ ꯋꯥꯈꯜ ꯅꯨꯡꯉꯥꯏꯇꯕꯥ ꯍꯟꯊꯍꯟꯅꯕꯥ ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ ꯁꯞꯂꯤꯃꯦꯟꯇ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯏ꯫

ꯑꯦꯒ꯭ꯔꯤꯀꯂꯆꯔ ꯑꯃꯁꯨꯡ ꯑꯦꯅꯚꯥꯏꯔꯅꯃꯦꯟꯇ ꯄ꯭ꯔꯣꯇꯦꯛꯁꯟ꯫

ꯕꯥꯏꯑꯣꯄꯦꯁ꯭ꯇꯤꯁꯥꯏꯗꯁꯤꯡ: ꯱.ꯀꯀꯆꯤꯡꯒꯤ ꯄꯥꯎꯗꯔ ꯃꯥꯏꯜꯗ ꯑꯃꯁꯨꯡ ꯇꯣꯃꯦꯇꯣ ꯒ꯭ꯔꯦ ꯃꯣꯜꯗꯀꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯏꯐꯦꯛꯇꯤꯚ ꯑꯣꯏꯕꯥ, ꯐꯤꯜꯗ ꯀꯟꯠꯔꯣꯂꯒꯤ ꯆꯥꯡ ꯑꯁꯤ 75%–85% ꯑꯣꯏ꯫

ꯐꯤꯗ ꯑꯦꯗꯤꯇꯤꯕ: ꯱.ꯃꯍꯧꯁꯥꯒꯤ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯛ ꯑꯣꯂꯇꯔꯅꯦꯇꯤꯚ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯏ, ꯂꯥꯏꯕꯁ꯭ꯇꯣꯛ ꯒ꯭ꯔꯣꯊ ꯄ꯭ꯔꯣꯃꯣꯠ ꯇꯧꯏ ꯑꯃꯁꯨꯡ ꯗꯥꯏꯔꯤꯌꯥꯒꯤ ꯊꯧꯗꯣꯛ ꯍꯟꯊꯍꯜꯂꯤ꯫

ꯑꯀꯣꯌꯕꯒꯤ ꯐꯤꯕꯃꯒꯤ ꯃꯆꯥꯀꯁꯤꯡ: ꯱.ꯏꯟꯗꯁ꯭ꯠꯔꯤꯒꯤ ꯑꯃꯣꯠꯄꯥ ꯏꯁꯤꯡꯗꯥ ꯍꯦꯚꯤ ꯃꯦꯇꯜ ꯑꯥꯏꯑꯣꯟ ꯑꯦꯗꯁꯣꯔꯁꯟ (ꯄꯤ.ꯕꯤ., ꯁꯤ.ꯑꯥꯔ.)ꯒꯤꯗꯃꯛꯇꯥ ꯁꯤꯖꯤꯟꯅꯩ, ꯃꯁꯤꯅꯥ ꯹꯰%ꯒꯤ ꯃꯊꯛꯇꯥ ꯂꯧꯊꯣꯀꯄꯒꯤ ꯆꯥꯡ ꯐꯪꯏ꯫

ꯀꯁ꯭ꯇꯃꯔꯁꯤꯡꯒꯤ ꯁꯔꯕꯤꯁꯁꯤꯡ꯫

ꯁ꯭ꯄꯦꯁꯤꯐꯤꯀꯦꯁꯟ ꯀꯁ꯭ꯇꯃꯔꯥꯏꯖꯦꯁꯟ: 1.1.꯴꯰%–꯹꯵% ꯏꯂꯥꯖꯤꯛ ꯑꯦꯁꯤꯗ ꯑꯃꯁꯨꯡ ꯱꯰%–꯳꯵% ꯄꯨꯅꯤꯀꯥꯂꯥꯖꯤꯟ ꯌꯥꯑꯣꯕꯥ ꯃꯄꯨꯡ ꯑꯣꯏꯕꯥ ꯄꯣꯠꯊꯣꯀꯁꯤꯡ ꯄꯤꯔꯤ, ꯃꯁꯤꯗꯥ ꯑꯣꯄꯁꯅꯦꯜ ꯗꯤꯀꯂꯔꯏꯖꯦꯁꯟ ꯑꯃꯁꯨꯡ ꯗꯤꯑꯣꯗꯣꯔꯥꯏꯖꯦꯁꯟ ꯇ꯭ꯔꯤꯠꯃꯦꯟꯇ ꯌꯥꯑꯣꯔꯤ꯫

ꯐꯣꯔꯃꯨꯂꯦꯁꯟ ꯗꯤꯕꯦꯂꯄꯃꯦꯟꯇ: ꯱.ꯀꯁꯃꯦꯇꯤꯛ ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯐꯥꯔꯃꯥꯁ꯭ꯌꯨꯇꯤꯀꯦꯜ ꯏꯟꯇꯔꯃꯦꯗꯤꯑꯦꯠꯁꯤꯡ ꯌꯥꯑꯣꯅꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯀꯁ꯭ꯇꯃꯁ ꯑꯣꯏꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯐꯣꯔꯃꯨꯂꯦꯁꯅꯁꯤꯡ ꯄꯤꯔꯤ꯫

ꯁꯔꯇꯤꯐꯤꯀꯦꯁꯟ ꯁꯄꯣꯔꯠ: 1.1.ꯁꯤ.ꯑꯣ.ꯑꯦ., ꯑꯦꯝ.ꯑꯦꯁ.ꯗꯤ.ꯑꯦꯁ., ꯑꯃꯁꯨꯡ ꯑꯣꯔꯒꯥꯅꯤꯛ ꯁꯔꯇꯤꯐꯤꯀꯦꯁꯅꯁꯤꯡ (ꯌꯨ.ꯑꯦꯁ.ꯗꯤ.ꯑꯦ./ꯑꯦꯟ.ꯑꯣ.ꯄꯤ.) ꯑꯁꯤ ꯔꯤꯛꯕꯦꯁ꯭ꯠ ꯇꯧꯔꯕꯥ ꯃꯇꯨꯡꯗꯥ ꯐꯪꯒꯅꯤ꯫